You should use The Depuffer consistently for at least four weeks to see results. That being said, in an independent clinical study, participants saw an immediate reduction in skin redness after using The Depuffer on irritated skin.

When developing the products, we used active ingredients from raw-material suppliers who could provide clinical data proving the effectiveness of their ingredients at specific levels. Then we formulated with those same levels. (FYI: In order to shout out specific active ingredients on their labels, some brands sprinkle a bit of the ingredients in their formulas instead of using them at the levels that were proven to be effective). Then, we hired a third-party facility to prove efficacy. They ran a clinical study of 26 subjects who used The Depuffer for four weeks. The Depuffer was clinically proven to reduce skin redness and undereye puffiness. In addition to the industry-standard tests above, we sent The Depuffer to 100 nerds who follow @shereeneidriss and asked them to take before and after videos and provide feedback.

No. The Depuffer does not treat rosacea. There isn't a single treatment that permanently gets rid of rosacea; rather, a combination of over-the-counter topicals and lasers can help mitigate the condition. That being said, The Depuffer has been clinically proven to improve transient skin flushing and reactive redness.

No. The Depuffer has been clinically proven to treat under-eye puffiness. For information about combating undereye circles, check out this article in the Nerd Academy blog.

Yes. There are two types of facial discoloration: hyperpigmentation and redness. Major Fade addresses the former; The Depuffer addresses the latter. More tactically speaking, when used together, Dr. Shereene Idriss recommends using The Depuffer in the morning first, followed by Major Fade Hyper Serum and Active Seal. In the evening, the Flash Mask should be applied first, then The Depuffer, prior to Hyper Serum and Active Seal.

Yes. For the average person, using several products with niacinamide at efficacy levels won’t irritate their skin, because it’s generally a well-tolerated ingredient. For individuals with sensitive skin, and in the undereye area, it's optimal to err on the side of caution and patch test, or to use only one product with niacinamide.

Yes. In a third party consumer perception study of 26 subjects, 96% said that The Depuffer is gentle for everyday use, and 88% said that their skin felt soothed and calmed after using The Depuffer. That being said, if you have sensitive skin, you should patch test before applying it fully.

The Depuffer contains Centella Asiatica, which gives the formula a brown hue. This is normal and to be expected.