Major Fade Hyper Serum brightening treatment pen with illuminating serum texture smear on black background
Close-up of Major Fade Hyper Serum being applied to skin to visibly brighten dark spots and boost glow
Before and after results showing improved skin tone and reduced forehead discoloration after eight weeks using the Major Fade Solution System
Major Fade Hyper Serum clinical results showing improved skin brightness, more even-looking tone, and reduced dark spots
Major Fade Hyper Serum ingredient highlights featuring kojic acid, alpha arbutin, niacinamide, and diglucosyl gallic acid
How to apply Major Fade Hyper Serum morning and night for dark spots and uneven skin tone
Dr. Shereene Idriss skincare tips for using Hyper Serum under makeup, on body discoloration, and under eyes
AM and PM skincare layering routine featuring Hyper Serum, Active Seal, Flash Mask, Soft Wash, and Disco Block SPF 50
Dr. Shereene Idriss holding Major Fade Hyper Serum with quote about treating discoloration at the source
Major Fade Hyper Serum and Active Seal moisturizer routine for dark spots and uneven skin tone
Customer reviews for Major Fade Hyper Serum highlighting improvements in post-acne marks, dark spots, and skin glow
Comparing the Left Un-Red Reducer Serum to the Major Fade Hyper Serum
How to refill the Hyper Serum applicator with a new cartridge
Major Fade Hyper Serum brightening treatment pen with illuminating serum texture smear on black background
Close-up of Major Fade Hyper Serum being applied to skin to visibly brighten dark spots and boost glow
Before and after results showing improved skin tone and reduced forehead discoloration after eight weeks using the Major Fade Solution System
Major Fade Hyper Serum clinical results showing improved skin brightness, more even-looking tone, and reduced dark spots
Major Fade Hyper Serum ingredient highlights featuring kojic acid, alpha arbutin, niacinamide, and diglucosyl gallic acid
How to apply Major Fade Hyper Serum morning and night for dark spots and uneven skin tone
Dr. Shereene Idriss skincare tips for using Hyper Serum under makeup, on body discoloration, and under eyes
AM and PM skincare layering routine featuring Hyper Serum, Active Seal, Flash Mask, Soft Wash, and Disco Block SPF 50
Dr. Shereene Idriss holding Major Fade Hyper Serum with quote about treating discoloration at the source
Major Fade Hyper Serum and Active Seal moisturizer routine for dark spots and uneven skin tone
Customer reviews for Major Fade Hyper Serum highlighting improvements in post-acne marks, dark spots, and skin glow
Comparing the Left Un-Red Reducer Serum to the Major Fade Hyper Serum
How to refill the Hyper Serum applicator with a new cartridge
(Video) Dermatologist Dr. Shereene Idriss explains how to use Hyper Serum and its key benefits
  • Bestseller

Major Fade Hyper Serum™

A hyperpigmentation serum for dullness, dark spots, sun damage, post-acne marks and uneven tone. Powered by alpha-arbutin and kojic acid, for brighter, more radiant skin.

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(1247)
For dullness, dark spots, age spots and post-acne marks
Alpha-arbutin and kojic acid fade spots at the source
93% said their complexion looked more even after 8 weeks*
Works on pigment across multiple pathways
Size
Full Size 0.96 oz/28 ml
Refills 0.96 oz/28 ml
Travel 0.51 oz/15 ml
Lightweight, great under makeup and the hype is real! My skin is smooth, even and glowing!
  • Dullness
  • Pigmentation
Vassiliki M Verified Buyer

Hyper Serum™ gives an instant glow the day you start, then fades the dark spots you can see and helps prevent new ones from forming.

Alpha-arbutin and kojic acid slow the pigment being made, 5% niacinamide keeps it from reaching the surface, diglucosyl gallic acid quiets the switch UV flips on, and licorice root calms the inflammation that starts it all.

Two sealed cartridges keep the actives fresh. Fragrance-free, for all skin types and tones.

  • Fades dark spots, sun spots and post-acne marks
  • Evens out dull, muddy uneven tone
  • Brightens dull skin
  • 5% niacinamide keeps it gentle enough for twice-daily use
  • Morning and night, on clean, dry skin.
  • Twist the pen to ON and click for 2–4 pumps. Massage over face.
  • Follow with Major Fade™ Active Seal™. Finish mornings with SPF 30+.
  • To refill: twist to ON, pull out the empty cartridge and snap in the new one after removing the cartridge overcap.
  1. Wash
  2. Treat
  3. Seal
  4. Protect
  • Byrdie Beauty Award 2023
  • Glamour Beauty Award 2023
  • TZR Beauty Groundbreakers 2024
  • Women's Health Skincare Award 2023
  • WWD Insider's Icons Award 2023
  • WWD Greatest Skincare 2024+C25
“I created Major Fade Hyper Serum after years of treating patients struggling with stubborn discoloration, post acne marks, and uneven skin tone. Having personally dealt with melasma myself, I know how frustrating persistent pigmentation can be. I wanted to create a targeted brightening serum that helps visibly fade discoloration while supporting healthy, radiant skin.”
Dr. Shereene Idriss Board-certified dermatologist
Major Fade Active Seal™
Major Fade Active Seal™
Vitamin C + Glutathione moisturizer for dullness + dark spots
$58.00
Product shot of the Solution System featuring Flash Mask, Hyper Serum and Active Seal
Major Fade Solution System™
The 3-step routine for dark spots + dullness
$165.00 ($174 value)

Major Fade Hyper Serum™

Hyperpigmentation serum for dark spots + dullness

$68.00

As seen in:

Skip the single-ingredient serums

Dark spots form in stages, and one ingredient can only reach one of them.

  • 0%Agree complexion appears more even-toned*
  • 0%Saw a visible reduction in dark spots*
  • Alpha ArbutinSlows tyrosinase, aka the enzyme that makes pigment, to fade dark spots and even tone
  • Kojic AcidHelps block tyrosinase, aka the pigment-making enzyme, to fade stubborn spots
  • NiacinamideSoothes and restores skin’s moisture barrier
  • Diglucosyl Gallic AcidVisibly decreases skin redness

Ingredients list

water/aqua/eau, niacinamide, glycerin, caprylic/capric triglyceride, pentylene glycol, alpha-arbutin, butyrospermum parkii (shea) butter, squalane, cetearyl olivate, dimethicone, cetyl alcohol, sorbitan olivate, kojic acid, diglucosyl gallic acid, glycyrrhiza glabra (licorice) root extract, persea gratissima (avocado) oil, sclerotium gum, xanthan gum, citric acid, sodium phytate, caprylyl glycol, hexylene glycol, ethylhexylglycerin, phenoxyethanol, mica, titanium dioxide (ci 77891)

*Based on a consumer perception study of 105 people using Major Fade Hyper Serum for 2 months.

Results you can see

★★★★★
Before / After

I thought having mature skin made this line not strong enough to do magic. I've followed Shereene on YT, watch her videos and it changed my life. I am one week in, I had glowing skin until I got diagnosed with Lupus, in one week my skin is literally glowing.

Melissa
Major Fade Hyper Serum™
★★★★★
Before / AfterBrown spots

Absolutely a holy grail product. After battling acne and hyperpigmentation from years of picking, this has drastically improved my skin tone, with no irritation in a very short amount of time.

Josephine D
Major Fade Hyper Serum™
★★★★★
Before / AfterBrown spots

I took before and after pictures of my skin because I wanted to be as objective as possible. After only 8 weeks I can physically see an improvement in my scars and sun spots.

Julie BVerified
Major Fade Hyper Serum™
★★★★★
Before / AfterAcne Scarring

I noticed a difference in my skin after only a month of use. Helps clear up hyperpigmentation after hormonal breakouts.

Evelyn DVerified
Hyper Serum Refills™
★★★★★
Before / AfterDark spots

My skin was a mess, inflamed, with constant chin break outs, my neck kept rashing up and worsening dark spots. It's been 5 months and my skin has never looked better, dark spots are fading very seldom do I get a break out.

Victoria GVerified
Hyper Serum Refills™
Dr. Shereene Idriss, MD

“Major Fade Hyper Serum comes with two cartridges to keep the active ingredients fresh, and it's safe to use alongside topical prescription medications. Your face, neck and chest are one cosmetic unit, so if you have discoloration on your chest, you can use Hyper Serum there too.

Tap one pump under your eyes to brighten dark circles. You don't need a separate hydrating serum with this one.”

Dr. Shereene Idriss, MD signature

Dr. Shereene Idriss, MD

Board-Certified Dermatologist

FAQs

What's the best serum for dull, uneven skin?

One that brightens now and fades spots over time.

Dr. Shereene Idriss, MD

Dull skin is often uneven tone you haven't named yet. Dr. Idriss Major Fade Hyper Serum gives an instant glow, then fades dark spots, sun spots and post-acne marks with alpha-arbutin and kojic acid, while niacinamide and licorice root keep skin calm enough for twice-daily use. Most people see a first difference around week 4.

It was created for all skin types and tones, and it's clinically tested to improve the look of skin tone. Melasma itself is a medical condition, so keep your dermatologist in the loop and use Major Fade alongside the care they prescribe.

Yes, but introduce one product at a time and patch test each product before you apply it fully. Be cautious with Major Fade Flash Mask, which contains exfoliating acids and may cause sensitivity for some people.

Major Fade is for any form of uneven skin tone: discoloration, hyperpigmentation, post-inflammatory redness, or the pigmentation left behind by chronic inflammation like acne or even eczema.

Give it time. Most people see a first difference around 4 weeks, and the real payoff in tone and dark spots at 6 to 8 weeks of sticking with it. Dark spots fade on consistency, not intensity, so the daily habit is the whole game.

All the products work individually to improve discoloration. For the best results, use them together because they're designed to work synergistically. Major Fade Hyper Serum has the most potent level of skin-brightening actives.

Yes, they play well together. Hyper Serum goes on first, then your retinoid, or alternate nights while your skin gets used to both. The one rule: skip your retinoid on Flash Mask nights so you're not overdoing it.

It was a deliberate choice. Everyone's tolerance for retinol is different, and Dr. Idriss believes retinol needs to be titrated to your skin's unique needs, both in concentration and in how often you use it. That's why we left it out and designed the routine to play nicely with whatever retinoid you already use.

Run this one by your own doctor, since every pregnancy is different and they know your history. Email hello@dridriss.com and we'll send the full ingredient list so you can go through it together.

It's a freshness thing. The full size is 0.96 oz split across two sealed 0.48 oz cartridges, so you only expose half the product to air at a time and the brightening actives stay stable.

Easy swap: twist the pen to ON, pull the empty cartridge back to pop it out, then push the new one in until it snaps into place. You get two cartridges in every Hyper Serum so your actives stay fresh instead of sitting out in the air.

 More FAQs

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