Dr. Idriss The Depuffer Roll-On Serum product shot with golden serum texture swatch on black background.
The Depuffer Roll-On Serum displayed on ice with text highlighting clinically proven reduction in under-eye puffiness.
Before-and-after comparison showing visible reduction in redness and puffiness after using The Depuffer Roll-On Serum.
Clinical results graphic for The Depuffer showing percentages of users reporting soothed irritation, refreshed skin, and reduced redness.
Ingredient-focused graphic highlighting arnica, centella asiatica, and niacinamide in The Depuffer Roll-On Serum.
Model applying The Depuffer Roll-On Serum with step-by-step instructions for rolling onto clean, dry skin.
Derm tips graphic featuring The Depuffer Roll-On Serum with recommendations for morning use, post-procedure care, and post-workout redness relief.
AM and PM skincare routine featuring The Depuffer alongside Hyper Serum, Active Seal, Flash Mask, and Disco Block SPF 50.
Portrait of Dr. Shereene Idriss holding The Depuffer Roll-On Serum with quote describing visible depuffing and refreshing benefits.
Customer review graphic highlighting 5-star reviews for The Depuffer Roll-On Serum and its benefits for puffiness and redness.
Close-up of The Depuffer metal roll-on applicator with text highlighting non-sticky hydrating serum texture.
Dr. Idriss The Depuffer Roll-On Serum product shot with golden serum texture swatch on black background.
The Depuffer Roll-On Serum displayed on ice with text highlighting clinically proven reduction in under-eye puffiness.
Before-and-after comparison showing visible reduction in redness and puffiness after using The Depuffer Roll-On Serum.
Clinical results graphic for The Depuffer showing percentages of users reporting soothed irritation, refreshed skin, and reduced redness.
Ingredient-focused graphic highlighting arnica, centella asiatica, and niacinamide in The Depuffer Roll-On Serum.
Model applying The Depuffer Roll-On Serum with step-by-step instructions for rolling onto clean, dry skin.
Derm tips graphic featuring The Depuffer Roll-On Serum with recommendations for morning use, post-procedure care, and post-workout redness relief.
AM and PM skincare routine featuring The Depuffer alongside Hyper Serum, Active Seal, Flash Mask, and Disco Block SPF 50.
Portrait of Dr. Shereene Idriss holding The Depuffer Roll-On Serum with quote describing visible depuffing and refreshing benefits.
Customer review graphic highlighting 5-star reviews for The Depuffer Roll-On Serum and its benefits for puffiness and redness.
Close-up of The Depuffer metal roll-on applicator with text highlighting non-sticky hydrating serum texture.
(Video) Dermatologist Dr. Shereene Idriss explains how to use The Depuffer Roll-On Serum and its key benefits
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The Depuffer™

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(1169)

Redness Reducing Roll-On Serum

Clinically proven to reduce facial puffiness
Your go-to for puffy, tired, overwhelmed skin
Arnica-based serum that visibly reduces swelling
Roll-on applicator delivers actives exactly where you need them
Price:
$38.00
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"I reach for this every morning. It visibly depuffs, refreshes, and lifts. The roll-on applicator with arnica works fast and my skin looks smoother and feels lighter."
Dr. Shereene Idriss
Founder
Puff be gone!
I tend to wake up with puffy eyes due to allergies, alcohol, or just general lack of sleep. The Depuffer has been a game changer in my AM routine. I roll the product all around my eyes and let sit while I have my coffee. Rolling on the upper eyelid feels SO GOOD!! My puff is reduced significantly by the time I'm ready to follow up with the rest of my routine.
Emily B
Verified Buyer
Amazing
Miracle worker!! I keep this in the fridge and use it in the am before I get ready. I am never without it!
Susan M
Verified Buyer

The first face roller that actively rolls away your problems. A deflushing, depuffing powerhouse serum clinically proven to relieve transient skin redness and minimize undereye puffiness. Supercharged with high-performance actives like arnica to reduce the look of swelling and centella asiatica to relieve visible facial redness.

Suitable for all skin types and tones. Clinically tested, dermatologist tested, fragrance-free, and non-irritating.

  • Apply anytime to clean dry skin.
  • Twist the roller “on,” gently squeeze, and glide over your skin to distribute a small amount of serum.
  • Twist “off,” and continue rolling to your heart’s content.
  • Pat in any excess. Allow to dry before applying other skincare products or makeup.
  • Allure Best of Beauty 2023
  • Harper's Bazaar Anti-Aging Award 2023
  • Marie Claire Beauty Award 2023
  • Marie Claire Skin Award 2023
  • Marie Claire Skin and Hair Award 2024
  • NewBeauty Annual Beauty Award 2024
  • Refinery29 Beauty Innovator 2023

Shipping
Free Shipping on US Orders $95+
Free Shipping on CA Orders $185+
Free Shipping on UK Orders £110+
Free Shipping on EU Orders €125+

Returns
We offer free returns within 30 days of delivery. To start a return or exchange, email hello@dridriss.com with your order number and return reason.

Read our full shipping and return policy here.

Results you can see

The Depuffer is clinically proven to reduce skin redness and undereye puffiness.*

*Based on an independent clinical and consumer perception study of 28 subjects after 5 mins and 4 weeks using The Depuffer

Clinical results for The Depuffer, before image
The Depuffer Week 1
Clinical results for The Depuffer showing a visible improvement in undereye puffiness and redness after 4 weeks
The Depuffer Week 4

Backed by science

92%

of users reported The Depuffer soothed the signs of irritation

92%

of users reported their skin felt refreshed

88%

of users reported a reduction in signs of redness

85%

of users reported their skin looked less puffy

Ingredients

What's inside

Arnica

Helps reduce the look of swelling

Centella Asiatica

Relieves visible facial redness

Niacinamide

Soothes and restores skin’s moisture barrier

Ash Bark Extract

Reduces puffiness

How to use The Depuffer

Application

Twist the roller “on,” gently squeeze, and glide over your skin to distribute a small amount of serum. Twist “off,” and continue rolling to your heart’s content. Pat in any excess serum. Allow to dry before applying other skincare products or makeup.

Frequency of use

You can apply The Depuffer anytime to clean dry skin.

a photo dispensing The Depuffer serum on a finger

Tips from Dr. Idriss

Use after sweaty seshes to deflush- for all types of extracurricular activities. :)

Apply after dermatological procedures to speed up recovery.

Gently roll serum outwards and upwards when applying under eyes.

FAQs

The Depuffer is suitable for all skin types. It has a gel-like consistency, so it's appropriate even for oily skin.

Yes. In a third party consumer perception study of 26 subjects, 96% said that The Depuffer is gentle for everyday use, and 88% said that their skin felt soothed and calmed after using The Depuffer. That being said, if you have sensitive skin, you should patch test before applying it fully.

You should use The Depuffer consistently for at least four weeks to see results. That being said, in an independent clinical study, participants saw an immediate reduction in skin redness after using The Depuffer on irritated skin.

Yes. For the average person, using several products with niacinamide at efficacy levels won’t irritate their skin, because it’s generally a well-tolerated ingredient. For individuals with sensitive skin, and in the undereye area, it's optimal to err on the side of caution and patch test, or to use only one product with niacinamide.

That's exactly where it shines. Gently roll outward and upward, and keep the serum out of your eyes themselves.

Rosacea deserves a doctor's care, so no, it does not treat it. What it is clinically shown to do is improve the look of transient redness and flushing, which many people with reactive skin appreciate.

No. Dark circles come from pigment or shadow, while The Depuffer targets under-eye puffiness and the look of redness, which it has been clinically shown to reduce. If dark circles are your main concern, our guide to dark circles on the Nerd Academy blog breaks down what actually helps.

That scent is the arnica itself. The Depuffer is fragrance free, and we don't add masking fragrance to cover up what real actives smell like, so what you're smelling is pure arnica at a level that actually works. The natural herbal scent is completely normal. We'd rather be honest about it than add fragrance to a product made for reactive, easily irritated skin.

Fresh face first. Apply it any time on freshly washed, dry skin and let it dry before other products or makeup. In the Major Fade routine, it goes on before Hyper Serum and Active Seal.

Yes. There are two types of facial discoloration: hyperpigmentation and redness. Major Fade addresses the former; The Depuffer addresses the latter. When using them together, Dr. Shereene Idriss recommends applying The Depuffer first in the morning, followed by Hyper Serum and Active Seal. In the evening, apply Flash Mask first, then The Depuffer, before Hyper Serum and Active Seal.

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